Concepedia

Solid-Phase Synthesis of Some Alkyl Hydrogen Methylphosphonates

Hubert Barucki, Robin M. Black, K. I. Kinnear, Ian Holden, Robert W. Read, Christopher M. Timperley

Phosphorus, sulfur, and silicon and the related elements · 2003 · 22 citations · 10 references

DOI

Concepts

Abstract

Eleven alkyl hydrogen methylphosphonates of structure RO(HO) P(O)Me were made by phosphoramidite chemistry on hydroxymethyl polystyrene resin; R = Me, Et, n -Pr, i -Pr, n -Bu, n -hexyl, n -octyl, cyclohexyl, cycloheptyl, cyclooctyl, and 3,3-dimethylbutan-2-yl ie. pinacolyl or Me 3 C--CH(Me)--.

References

10

Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation

Steven V. Ley, Ian R. Baxendale, Robert N. Bream et al. · Journal of the Chemical Society Perkin Transactions 1 · 2000 · 689 citations · Full text

, , +13

Report on 640 Victims of the Tokyo Subway Sarin Attack

Tetsu Okumura, N. Takasu, Shinichi Ishimatsu et al. · Annals of Emergency Medicine · 1996 · 632 citations

, , +5

Application of gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry to the analysis of chemical warfare samples, found to contain residues of the nerve agent sarin, sulphur mustard and their degradation products

Robin M. Black, R.J. Clarke, Robert W. Read et al. · Journal of Chromatography A · 1994 · 300 citations

, , +16

Rapid screening procedures for the hydrolysis products of chemical warfare agents using positive and negative ion liquid chromatography–mass spectrometry with atmospheric pressure chemical ionisation

Robert W. Read, Robin M. Black · Journal of Chromatography A · 1999 · 120 citations

, , +17

Oligodeoxynucleoside methylphosphonates: synthesis and enzymic degradation

Sudhir Agrawal, John Goodchild · Tetrahedron Letters · 1987 · 98 citations

, , +13