Concepedia

Pharmacokinetic study of methotrexate, folinic acid and their serum metabolites in children treated with high-dose methotrexate and leucovorin rescue

C. Wolfrom, R. Hepp, R. Hartmann, H. Breithaupt, G. Henze

European Journal of Clinical Pharmacology · 1990 · 45 citations · 47 references

DOI

Concepts

References

47

Chemistry and biology of pteridines

C. Fromageot · Biochimica et Biophysica Acta · 1956 · 1.2K citations

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7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.

Samuel A. Jacobs, Ronald G. Stoller, Bruce A. Chabner et al. · Journal of Clinical Investigation · 1976 · 256 citations · Full text

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STUDIES ON THE IDENTIFICATION OF A FOLATE COMPOUND OF HUMAN SERUM*

Victor Herbert, Allan R. Larrabee, John M. Buchanan · Journal of Clinical Investigation · 1962 · 229 citations · Full text

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Pharmacokinetics of the diastereoisomers of leucovorin after intravenous and oral administration to normal subjects.

James A. Straw, Daniele Szapary, William T. Wynn · PubMed · 1984 · 140 citations

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A comparative study on the pharmacokinetics of methotrexate in a dose range of 0.5 g to 33.6 g/m2 in children with acute lymphoblastic leukemia

Joseph D. Borsi, Peter Johan Moe · Cancer · 1987 · 123 citations

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