Changes in Vitamin D and Parathyroid Hormone Metabolism in Incident Pediatric Crohnʼs Disease

Abstract

Incident CD was associated with 25(OH)D and 1,25(OH)2D deficiency and a relative hypoparathyroidism that resolved following diagnosis. Inflammatory cytokine suppression of PTH and renal 1-α-hyroxylase may contribute to these alterations.