Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: Comparative analyses with ADAMTS-5, -9, -16 and -18

Molecular modeling of protein-glycosaminoglycan interactions.

A D Cardin, Herschel J. R. Weintraub · Arteriosclerosis An Official Journal of the American Heart Association Inc · 1989 · 1.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis

S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Nature · 2005 · 1.3K citations

Dentistry, Genetics, Molecular Genetics +14

ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

Heather Stanton, Fraser M. Rogerson, Charlotte J. East et al. · Nature · 2005 · 915 citations

Medicine, Molecular Biology, Orthopaedic Surgery +14

Cloning and Characterization of ADAMTS11 , an Aggrecanase from the ADAMTS Family

Ilgar Abbaszade, Rui‐Qin Liu, Fude Yang et al. · Journal of Biological Chemistry · 1999 · 489 citations · Full text

Medicine, Biochemistry, Molecular Biology +17

Versican V1 Proteolysis in Human Aorta in Vivo Occurs at the Glu441-Ala442 Bond, a Site That Is Cleaved by Recombinant ADAMTS-1 and ADAMTS-4

John D. Sandy, Jennifer Westling, Richard D. Kenagy et al. · Journal of Biological Chemistry · 2001 · 457 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13