Concepedia

Effect of ketoconazole on cholesterol synthesis and on HMG-COA reductase and LDL-receptor activities in Hep G2 cells

H.J.M. Kempen, Kees Van Son, Louis Cohen, Marieke Griffioen, Hans Verboom, Louis M. Havekes

Biochemical Pharmacology · 1987 · 41 citations · 19 references

DOI

Concepts

References

19

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

Michael S. Brown, J R Faust, Joseph L. Goldstein et al. · Journal of Biological Chemistry · 1978 · 557 citations · Full text

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Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes.

David S. Loose, Patricia B. Kan, M Hirst et al. · Journal of Clinical Investigation · 1983 · 446 citations · Full text

, , +17

Ketoconazole blocks testosterone synthesis

Allan Pont · Archives of Internal Medicine · 1982 · 352 citations

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Ketoconazole Blocks Testosterone Synthesis

Archives of Internal Medicine · 1982 · 296 citations

, , +17

Site of Action of Low Dose Ketoconazole on Androgen Biosynthesis in Men*

Richard J. Santen, H. Van den Bossche, J. Symoens et al. · The Journal of Clinical Endocrinology & Metabolism · 1983 · 231 citations

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