Publication | Closed Access
Studies on the Alkylation of Derivatives of Guanines
40
Citations
49
References
1989
Year
Derivative (Chemistry)DerivativesN9-substituted Guanine AnalogsOrganic ChemistryRelative FormationN9 IsomersChemistryHeterocycle ChemistryPharmacologyChemical DerivativeSynthetic ChemistryNatural Product Synthesis
Abstract The synthesis of some N7- and N9-substituted guanine analogs was investigated. The influence of the base, the alkylating agent and of the type of derivatization of the purine moiety on the relative formation of the N7 and N9 isomers was studied.
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