A leptin missense mutation associated with hypogonadism and morbid obesity

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Congenital leptin deficiency is associated with severe early-onset obesity in humans

Carl Montague, I. Sadaf Farooqi, Jonathan P. Whitehead et al. · Nature · 1997 · 2.9K citations · Full text

Medicine, Endocrinology, Pediatrics +11

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

Farid Chehab, Mary E. Lim, Ronghua Lu · Nature Genetics · 1996 · 1.5K citations

Veterinary Medicine, Endocrinology, Genetics +12

The Value of Cardiovascular Autonomic Function Tests: 10 Years Experience in Diabetes

D J Ewing, Christopher Martyn, Robert J. Young et al. · Diabetes Care · 1985 · 1.4K citations

Medicine, Internal Medicine, Physiology +17

Sympathetic skin response--a method of assessing unmyelinated axon dysfunction in peripheral neuropathies.

Bhagwan T. Shahani, John Halperin, P. Boulu et al. · Journal of Neurology Neurosurgery & Psychiatry · 1984 · 600 citations · Full text

Medicine, Neurology, Neuroscience +11