Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Roger Stupp, Warren Mason, Martin J. van den Bent et al. · New England Journal of Medicine · 2005 · 21.6K citations · Full text

Medicine, Oncology, Radiation Oncology +12

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

Julie R. Brahmer, Charles G. Drake, Ira Wollner et al. · Journal of Clinical Oncology · 2010 · 2.9K citations · Full text

Medicine, Oncology, Pharmacology +17

Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

Md. Zahidunnabi Dewan, Ashley E. Galloway, Noriko Kawashima et al. · Clinical Cancer Research · 2009 · 1.6K citations · Full text

Medicine, Oncology, Radiation Oncology +17

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

Andrew T. Parsa, James S. Waldron, Amith Panner et al. · Nature Medicine · 2006 · 1.4K citations

Medicine, Cancer Biology, Oncology +14

Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

Sandra Demaria, Noriko Kawashima, Anne Marie Yang et al. · Clinical Cancer Research · 2005 · 1K citations · Full text

Medicine, Immunology, Oncology +17