Mesenchymal Stem-Cell Immunosuppressive Capabilities: Therapeutic Implications in Islet Transplantation

Abstract

Mesenchymal stem cells (MSCs) are known to be capable of suppressing immune responses and offer therapeutic potential for achieving transplantation tolerance. This review will discuss the impacts of MSCs on transplant immunity and focus on the potential role of MSCs in protecting islet grafts from both rejection and autoimmune attack.