Biometrika · 1986 · 1.4K citations · 14 references
Public HealthBiostatisticsCausal InferenceEpidemiologic MethodsEpidemiologyAnalytic EpidemiologyCase-control StudiesCohort AnalysisCohort StudiesMissing Covariate DataPrevention TrialsRelative Risk Estimation
Cohort studies follow individuals to relate failure rates to prior covariate histories. The authors propose a case‑cohort design that collects covariate data only for failures and a random subcohort. They present odds‑ratio and relative‑risk estimation procedures for the design and evaluate them in a small simulation comparing to full‑cohort and synthetic case‑control analyses. The design’s relevance to epidemiologic cohort studies and disease‑prevention trials is highlighted.
Suppose that a cohort of individuals is to be followed in order to relate failure rates to preceding covariate histories. A design is proposed which involves covariate data only for cases experiencing failure and for members of a randomly selected ubcohort. Odds ratio and relative risk estimation procedures are presented for such a ‘case-cohort’ design. A small simulation study compares ease-cohort relative risk estimation procedures to full-cohort and synthetic case-control analyses. Relevance to epidemiologic cohort studies and disease prevention trials is discussed.
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Covariance Analysis of Censored Survival Data
N. E. Breslow · Biometrics · 1974 · 1.8K citations
Logistic disease incidence models and case-control studies
Ross L. Prentice, Ronald Pyke · Biometrika · 1979 · 1.1K citations
Multiplicative Models and Cohort Analysis
N. E. Breslow, Jay H. Lubin, P. Marek et al. · Journal of the American Statistical Association · 1983 · 533 citations