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Synthesis and structure–activity relationship studies of 4-arylthiosemicarbazides as topoisomerase IV inhibitors with Gram-positive antibacterial activity. Search for molecular basis of antibacterial activity of thiosemicarbazides

Medicinal ChemistryAntimicrobial Drug DiscoveryBiochemistryMedicineAntibacterial ActivityNatural SciencesAntibacterial AgentAntimicrobial ChemotherapyAntimicrobial CompoundAntimicrobial AgentsGram-positive Antibacterial ActivityPharmacologyPharmaceutical ChemistryDrug DiscoveryTopoisomerase Iv Inhibitors