TNF-α contributes to the development of allergic rhinitis in mice

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.

Paul S. Foster, Simon P. Hogan, Alistair J. Ramsay et al. · The Journal of Experimental Medicine · 1996 · 1.4K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

Richard Williams, Marc Feldmann, R N Maini · Proceedings of the National Academy of Sciences · 1992 · 986 citations

Medicine, Immunology, Pathobiology +12

Interleukin-4, -5, and -6 and Tumor Necrosis Factor-α in Normal and Asthmatic Airways: Evidence for the Human Mast Cell as a Source of these Cytokines

Peter Bradding, J A Roberts, K. Britten et al. · American Journal of Respiratory Cell and Molecular Biology · 1994 · 839 citations

Life Sciences, Immunology, Pathology +16

IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants.

Gianfranco Del Prete, Enrico Maggi, Paola Parronchi et al. · The Journal of Immunology · 1988 · 715 citations · Full text

Life Sciences, Cell Biology, Immunology +16

IL-4 is required to generate and sustain in vivo IgE responses.

Fred D. Finkelman, Ildy M. Katona, Joseph F. Urban et al. · The Journal of Immunology · 1988 · 679 citations · Full text

Life Sciences, Immunology, Hypersensitivity +15