A facile enzymatic resolution process for the preparation of (+)--2-(6-hethoxy-2-naphthyl)propionic acid (Naproxen).

Quantitative analyses of biochemical kinetic resolutions of enantiomers

Ching Shih Chen, Yoshitaka Fujimoto, Gary Girdaukas et al. · Journal of the American Chemical Society · 1982 · 2.6K citations

Natural Sciences, Biochemistry, Chemistry +9

Nonsteroidal antiinflammatory agents. I. 6-Substituted 2-naphthylacetic acids

Ian T. Harrison, B. M. Lewis, Peter A. Nelson et al. · Journal of Medicinal Chemistry · 1970 · 244 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7

Perspectives in Nonsteroidal Anti‐inflammatory Agents

T. Y. Shen · Angewandte Chemie International Edition in English · 1972 · 224 citations

Medicine, Medicinal Chemistry, Pharmacology +14

ANTI-INFLAMMATORY AND ANALGETIC PROPERTIES OF d-2-(6'-METHOXY-2'-NAPHTHYL)-PROPIONIC ACID (NAPROXEN)

Adolph P. Roszkowski, Wendell H. Rooks, A. J. TOMOLONIS et al. · Journal of Pharmacology and Experimental Therapeutics · 1971 · 147 citations

Medicine, Pharmacology, Pharmacotherapy +15

Enzymatic inversion at saturated carbon: Nature and mechanism of the inversion of R(−) p-iso-butyl hydratropic acid

William J. Wechter, David G. Loughhead, Robert J. Reischer et al. · Biochemical and Biophysical Research Communications · 1974 · 133 citations

Life Sciences, Biochemistry, Chemistry +7