YAC128 Huntington׳s disease transgenic mice show enhanced short-term hippocampal synaptic plasticity early in the course of the disease

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Neuropathological Classification of Huntingtonʼs Disease

Jean‐Paul Vonsattel, Richard H. Myers, Thomas J. Stevens et al. · Journal of Neuropathology & Experimental Neurology · 1985 · 2.6K citations

Medicine, Neurology, Neuroscience +17

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

Michael Saxe, Fortunato Battaglia, Jing-Wen Wang et al. · Proceedings of the National Academy of Sciences · 2006 · 1K citations

Medicine, Neurobiology, Neuroscience +17

A role for adult neurogenesis in spatial long-term memory

Jason S. Snyder, N.S. Hong, Robert J. McDonald et al. · Neuroscience · 2004 · 844 citations

Medicine, Neurobiology, Neuroscience +14

A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

John Hodgson, N. Agopyan, Claire‐Anne Gutekunst et al. · Neuron · 1999 · 831 citations · Full text

Life Sciences, Genetics, Neuroscience +13