Concepedia

Comparison of Monoclonal and Polyclonal ELISAs for Fecal Elastase in Patients With Cystic Fibrosis and Pancreatic Insufficiency

Drucy Borowitz, Rong Lin, Susan S. Baker

Journal of Pediatric Gastroenterology and Nutrition · 2007 · 38 citations · 12 references

DOI

Abstract

The positive predictive value of both monoclonal and polyclonal fecal elastase in patients with cystic fibrosis is extremely good; however, correlation of either test with CFA was poor. The median value for the polyclonal elastase assay is higher than for the monoclonal assay, which could potentially lead to lower sensitivity of the polyclonal assay at lower cutpoints for the monoclonal assay is used.

References

12

RAPID METHOD FOR THE DETERMINATION OF FAT IN FECES

J. H. Van De Kamer, H. ten Bokkel Huinink, H. A. Weyers · Journal of Biological Chemistry · 1949 · 1.9K citations · Full text

, , +15

Improved respiratory prognosis in patients with cystic fibrosis with normal fat absorption

Kevin Gaskin, Denis Gurwitz, Peter R. Durie et al. · The Journal of Pediatrics · 1982 · 280 citations

, , +7

How useful is fecal pancreatic elastase 1 as a marker of exocrine pancreatic disease?

Satti Beharry, Lynda Ellis, Mary Corey et al. · The Journal of Pediatrics · 2002 · 141 citations

, , +4

Use of fecal elastase-1 to classify pancreatic status in patients with cystic fibrosis

Drucy Borowitz, Susan S. Baker, Linda C. Duffy et al. · The Journal of Pediatrics · 2004 · 114 citations

, , +5

A comparison of the efficacy and tolerance of pancrelipase and placebo in the treatment of steatorrhea in cystic fibrosis patients with clinical exocrine pancreatic insufficiency

Robert C. Stern, Jay D. Eisenberg, J. Wagener et al. · The American Journal of Gastroenterology · 2000 · 84 citations