Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Roger Stupp, Warren Mason, Martin J. van den Bent, +16

New England Journal of Medicine

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

Roger Stupp, Monika E. Hegi, Warren Mason, +21

The Lancet Oncology

5-Year AnalysisNeuro-oncologyOncologyRadiation TherapyAdjuvant Temozolomide +6

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon, +6

Nature

Genome InstabilityRadiation TherapyMedicineRadiation EffectGlioma Stem Cells +10

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

David L. Porter, Bruce L. Levine, Michael Kalos, +2

New England Journal of Medicine

Chimeric Antigen ReceptorChronic Lymphoid LeukemiaAutoimmune DiseaseLymphocyte DevelopmentImmunology +11

Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2

Richard A. Morgan, James C. Yang, Mio Kitano, +3

Molecular Therapy

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.

Zelig Eshhar, Tova Waks, G. Gross, +1

Proceedings of the National Academy of Sciences

Chimeric GenesImmunologyImmunodominanceImmunologic MechanismAntigen Processing +15

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

Martin Pulé, Barbara Savoldo, Gary D. Myers, +13

Nature Medicine

Cancer ImmunosurveillanceAntitumor ActivityVirus-specific T CellsT-regulatory CellImmunology +7

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

John H. Sampson, Amy B. Heimberger, Gary E. Archer, +13

Journal of Clinical Oncology

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

Anastasia Murat, Eugenia Migliavacca, Thierry Gorlia, +17

Journal of Clinical Oncology

Induction of CD8⁺T-Cell Responses Against Novel Glioma–Associated Antigen Peptides and Clinical Activity by Vaccinations With α-Type 1 Polarized Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Patients With Recurrent Malignant Glioma

Hideho Okada, Paweł Kaliński, Ryo Ueda, +17

Journal of Clinical Oncology