Adrenergic Signaling Regulates Mitochondrial Ca <sup>2+</sup> Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca <sup>2+</sup> Uniporter - Concepedia

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Adrenergic Signaling Regulates Mitochondrial Ca <sup>2+</sup> Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca <sup>2+</sup> Uniporter

DOI Full Paper Access

87

Citations

58

References

2014

Year

Jin O‐Uchi, Bong Sook Jhun, Shangcheng Xu, Stephen Hurst, Anna Raffaello, Xiaoyun Liu, Huiliang Zhang, Polina Gross, Jyotsna Mishra, Alina Ainbinder,

Antioxidants and Redox Signaling

Abstract

The α1-AR-Pyk2-dependent tyrosine phosphorylation of the MCU regulates mitochondrial Ca2+ entry and apoptosis in cardiac cells.

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