Concepedia

Carriage of stx2a Differentiates Clinical and Bovine-Biased Strains of Escherichia coli O157

Smriti Shringi, Carrie Schmidt, K. N. Mui Katherine, Kelly A. Brayton, Dale D. Hancock, Thomas E. Besser

PLoS ONE · 2012 · 39 citations · 47 references

DOIFull text

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Abstract

Presence or absence of stx2a (or another product encoded by the Stx2a-associated bacteriophage) is a parsimonious explanation for differential virulence of BBG and CG, as reflected in the distributions of these genotypes in humans and in the cattle reservoir.

References

47

Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

Flemming Scheutz, Louise D. Teel, Lothar Beutin et al. · Journal of Clinical Microbiology · 2012 · 802 citations · Full text

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<i>Escherichia coli</i>Harboring Shiga Toxin 2 Gene Variants: Frequency and Association with Clinical Symptoms

Alexander W. Friedrich, Martina Bielaszewska, Wenlan Zhang et al. · The Journal of Infectious Diseases · 2002 · 720 citations · Full text

Variation in virulence among clades of <i>Escherichia coli</i> O157:H7 associated with disease outbreaks

Shannon D. Manning, Alifiya S. Motiwala, A. Cody Springman et al. · Proceedings of the National Academy of Sciences · 2008 · 445 citations · Full text

Use of the flagellar H7 gene as a target in multiplex PCR assays and improved specificity in identification of enterohemorrhagic Escherichia coli strains

Victor P. J. Gannon, S.F. D’Souza, T. Graham et al. · Journal of Clinical Microbiology · 1997 · 367 citations · Full text

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Sequence of Shiga Toxin 2 Phage 933W from<i>Escherichia coli</i>O157:H7: Shiga Toxin as a Phage Late-Gene Product

Guy Plunkett, Debra J. Rose, T. Durfee et al. · Journal of Bacteriology · 1999 · 357 citations · Full text