Concepedia

High Glucose Up-Regulates ENaC and SGK1 Expression in HCD-Cells

Claire E. Hills, Rosemary Bland, Jeanette Bennett, Pierre Ronco, Paul E. Squires

Cellular Physiology and Biochemistry · 2006 · 52 citations · 35 references

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Abstract

Together these data offer a potential explanation for glucose-evoked Na+-resorption and a potential contributory role of SGK1 and ENaCs in development of secondary hypertension, commonly linked to diabetic nephropathy.

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