Synthetic pores with reactive signal amplifiers as artificial tongues

A biosensor that uses ion-channel switches

Bruce Cornell, V. L. B. Braach‐Maksvytis, Lionel G. King et al. · Nature · 1997 · 1.1K citations

Engineering, Biosensing Systems, Bioelectronics +6

Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines

Lindsey J. Macpherson, Adrienne E. Dubin, Michael J. Evans et al. · Nature · 2007 · 1.1K citations · Full text

Molecular Pharmacology, Signal Transduction, Molecular Physiology +14

Stochastic sensing of organic analytes by a pore-forming protein containing a molecular adapter

Li‐Qun Gu, Orit Braha, Sean Conlan et al. · Nature · 1999 · 707 citations

Molecular Adapter, Engineering, Biosensing Systems +9

Synthetic molecules that fold into a pleated secondary structure in solution

R. Scott Lokey, Brent L. Iverson · Nature · 1995 · 535 citations

Supramolecular Assembly, Engineering, Natural Sciences +7

Molecular Tweezers and Clips as Synthetic Receptors. Molecular Recognition and Dynamics in Receptor−Substrate Complexes

Frank‐Gerrit Klärner, B. Kahlert · Accounts of Chemical Research · 2003 · 371 citations