Simultaneous Determination of Genomic DNA Methylation and Uracil Misincorporation - Concepedia

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Publication | Open Access

Simultaneous Determination of Genomic DNA Methylation and Uracil Misincorporation

DOI Full Paper Access

26

Citations

10

References

2009

Year

Abalo Chango, Afif M. Abdel Nour, Céline Niquet, Frédéric J. Tessier

Medical Principles and Practice

Abstract

Our results confirm that the HPLC/ESI-MS method reported earlier for measuring 5-metC allows measurement of uracil misincorporation into DNA.

References

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Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage Benjamin C. Blount, M. M. Mack, Carol M. Wehr, Proceedings of the National Academy of Sciences ChromatinGenome InstabilityFolate DeficiencyDna DamageGenetic Disorder	1997	1.4K
Hypomorphism for RPGRIP1L, a Ciliary Gene Vicinal to the FTO Locus, Causes Increased Adiposity in Mice George Stratigopoulos, Jayne F. Martin Carli, Diana R. O’Day, Cell Metabolism Knockout MouseMetabolic SyndromeDevelopmental BiologyMetabolic DisorderGenetics	2014	154
Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro Jimmy W. Crott, Susan T. Mashiyama, Bruce N. Ames, Carcinogenesis	2001	106
Interference with DNA Methyltransferase Activity and Genome Methylation during F9 Teratocarcinoma Stem Cell Differentiation Induced by Polyamine Depletion L Frostesjö, Ingvar Holm, Birgitta Grahn, Journal of Biological Chemistry	1997	82
Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes Susan T. Mashiyama, Chantal Courtemanche, Ilan Elson‐Schwab, Analytical Biochemistry ChromatinImproved AssayBiochemistryNatural SciencesBiochemical Genetics	2004	50
On the nature of folic‐acid‐sensitive fragile sites in human chromosomes: An hypothesis Carlos L. Krumdieck, Patricia N. Howard‐Peebles, John M. Opitz American Journal of Medical Genetics	1983	45
The Role of Vitamin B12 and Folate in Carcinogenesis Victor Herbert Vitamin NutritionOncogenic AgentVitamin B12Vitamin B ComplexRadiation Oncology	1986	33
Uracil in Human DNA from Subjects with Normal and Impaired Folate Status As Determined by High-Performance Liquid Chromatography−Tandem Mass Spectrometry Jicun Ren, Arve Ulvik, Helga Refsum, Analytical Chemistry	2001	29
Quantitative methylation-sensitive arbitrarily primed PCR method to determine differential genomic DNA methylation in down syndrome Abalo Chango, Latifa Abdennebi‐Najar, Frédéric J. Tessier, Biochemical and Biophysical Research Communications Down SyndromeGenetic AnalysisGenetic DisorderPcr MethodGenetics	2006	16
Nucleic acid composition of bone marrow mononuclear cells in cobalamin deficiency BH Ramsahoye, AK Burnett, Christine Taylor Blood	1996	13

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