Chemoprotection against Three Modes of Radiation Death in the Mouse

Abstract

SummarySeven radioprotective agents have been tested for their ability to protect the mouse against three radiation-induced modes of death. Six of the seven agents offer relatively less protection against gastrointestinal death than against haematopoietic death, and only one (PAPP) is effective against CNS death. It is proposed that the variations in protection against the three forms of death may be the result of tissue-specific differences in the ability to concentrate and respond to each agent.