Biopolymers · 1969 · 100 citations · 23 references
Life SciencesBiochemistryBiophysicsMolecular BiophysicsMolecular PhysicsProtein BiochemistryCasein ChemistryMacromolecular AssemblyProtein ConformationProtein DenaturationProtein DynamicsProtein StructureCasein AggregationCasein DenaturationPartial Molar VolumePressure-induced DenaturationProtein Conformational ChangesReversible Conformational Changes
Abstract The effect of pressure on the temperature‐dependent association of β‐casein was studied by the method of light scattering. Between 1 and 1500 kg/cm 2 , β‐casein is reversibly depolymerized, indicating an increase in partial specific volume of the protein with association. Possible mechanisms for association are discussed. At still higher pressures reversible reassociation is observed, which is ascribed to conformational changes in the β‐casein molecule.
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Physical chemistry of macromolecules
Choice Reviews Online · 2007 · 3.8K citations
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Terrell L. Hill, J. J. Gillis · Physics Today · 1961 · 2.2K citations
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W. H. Stockmayer · The Journal of Chemical Physics · 1950 · 416 citations