Concepedia

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

Juan A. Bernal, Rosa Luna, Águeda G. Espina, Icíar Lázaro, Francisco Ramos‐Morales, Francisco Romero, Carmen Arias, Augusto Silva, Marı́a Tortolero, José A. Pintor‐Toro

Nature Genetics · 2002 · 197 citations · 24 references

DOI

Concepts

References

24

WAF1, a potential mediator of p53 tumor suppression

Wafik S. El‐Deiry, Takashi Tokino, Victor E. Velculescu et al. · Cell · 1993 · 8.4K citations

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Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner, Jennifer A. Pietenpol, Sam Thiagalingam et al. · Nature · 1993 · 1.5K citations

, , +16

Mutator phenotype may be required for multistage carcinogenesis.

L A Loeb · PubMed · 1991 · 1.3K citations

, , +11

Is a p53-Regulated Inhibitor of G2/M Progression

Heiko Hermeking, Christoph Lengauer, Kornélia Polyák et al. · Molecular Cell · 1997 · 1.2K citations · Full text

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