Archives of Dermatology and Syphilology · 1925 · 14 citations · 0 references
MedicineDermatologyPathologyAnatomic PathologyDermatopathologyHistopathologyGranulomatous DermatitisGranulomatous DermatosesGranulomatous InflammationImmunopathology Of SkinInfectious DermatosesInflammatory DermatosesCutaneous Granulomatous DermatitisGranulomatous EruptionsGranulomatous LesionsGranulomatous Skin InflammationInoculationSarcoid GranulomasSarcoidal DermatitisSarcoidal Granulomatous Dermatitis
The patient whose case history appears herein presented a generalized eruption of such extraordinary character that it was deemed worthy of report. A negress, aged 23, presented a diffuse generalized papular, squamous, nodular eruption (Figs. 1 and 2). The lesions were psoriasiform and infiltrated; some were annular, and others followed the natural line of cleavage of the skin. In the course of twenty-one months, almost all of the lesions involuted, with scar formation, some with prior ulceration. The scars were soft and pliable, resembling the scars of syphilids (Figs. 5 and 6). There were constitutional and objective symptoms of an infection, the nature of which was undetermined. Histologically, the picture was that of a granuloma (Fig. 3). Laboratory and animal inoculation studies were negative. No definite clinical diagnosis was made. Indeed, the diagnosis of the eruption was puzzling to all of the dermatologists<sup>1</sup>who observed the patient during her