Muscarinic M2 receptors mediate transactivation of EGF receptor through Fyn kinase and without matrix metalloproteases

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

Norbert Prenzel, Esther Zwick, Henrik Daub et al. · Nature · 1999 · 1.5K citations

Signal Transduction, Molecular Physiology, Egf Receptor Transactivation +10

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

Henrik Daub, Christian Wallasch, Axel Ullrich · Nature · 1996 · 1.5K citations

Signal Transduction, Developmental Biology, Molecular Physiology +10

Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor α

Thomas Garrett, Neil M. McKern, Meizhen Lou et al. · Cell · 2002 · 778 citations · Full text

Crystal Structure, Signal Transduction, Receptor (Biochemistry) +6

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

Masanori Asakura, Masafumi Kitakaze, Seiji Takashima et al. · Nature Medicine · 2002 · 718 citations

Adam12 Processing, Cardiac Muscle, Cardiomyopathy +9

Signal characteristics of G protein-transactivated EGF receptor

Henrik Daub · The EMBO Journal · 1997 · 662 citations · Full text

Signal Transduction, Growth Hormone, Human Growth +6