Concepedia

Cordycepin (3′-deoxyadenosine) inhibits the growth of B16-BL6 mouse melanoma cells through the stimulation of adenosine A3 receptor followed by glycogen synthase kinase-3β activation and cyclin D1 suppression

Noriko Yoshikawa, Shizuo Yamada, Chihiro Takeuchi, Satomi Kagota, Kazumasa Shinozuka, Masaru Kunitomo, Kazuki Nakamura

Naunyn-Schmiedeberg s Archives of Pharmacology · 2007 · 65 citations · 15 references

DOI

Concepts

References

15

Cordycepin, a Metabolic Product isolated from Cultures of Cordyceps militaris (Linn.) Link.

K. G. Cunningham, William Manson, F. S. Spring et al. · Nature · 1950 · 341 citations

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The A3 Adenosine Receptor Is Highly Expressed in Tumor <b> <i>versus</i> </b> Normal Cells

Lea Madi, Avivit Ochaion, Lea Rath‐Wolfson et al. · Clinical Cancer Research · 2004 · 191 citations · Full text

, , +17

Antitumor effect of cordycepin (3'-deoxyadenosine) on mouse melanoma and lung carcinoma cells involves adenosine A3 receptor stimulation.

Kazuki Nakamura, Noriko Yoshikawa, Yu Yamaguchi et al. · PubMed · 2006 · 167 citations

, , +11

The apoptotic effect of cordycepin on human OEC-M1 oral cancer cell line

Wei-Ciao Wu, Jenn-Ren Hsiao, Yu-Yan Lian et al. · Cancer Chemotherapy and Pharmacology · 2006 · 124 citations

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A3 Adenosine Receptor Activation Inhibits Cell Proliferation via Phosphatidylinositol 3-Kinase/Akt-dependent Inhibition of the Extracellular Signal-regulated Kinase 1/2 Phosphorylation in A375 Human Melanoma Cells

Stefania Merighi, Annalisa Benini, Prisco Mirandola et al. · Journal of Biological Chemistry · 2005 · 122 citations · Full text

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