Inhibition of Mitochondrial Permeability Transition Prevents Sepsis-Induced Myocardial Dysfunction and Mortality

Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

Derek C. Angus, Walter T. Linde‐Zwirble, Jeffrey Lidicker et al. · Critical Care Medicine · 2001 · 8.6K citations

Veterinary Medicine, Infectious Diseases, Internal Medicine +16

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

Life Sciences, Cell Biology, Molecular Biology +17

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Christopher Baines, Robert A. Kaiser, Nicole H. Purcell et al. · Nature · 2005 · 2.2K citations

Life Sciences, Cell Biology, Molecular Biology +16

Association between mitochondrial dysfunction and severity and outcome of septic shock

David Brealey, M. P. Brand, Iain P. Hargreaves et al. · The Lancet · 2002 · 1.5K citations

Veterinary Medicine, Cell Biology, Pathobiology +14

Reversing established sepsis with antagonists of endogenous high-mobility group box 1

Huan Yang, Mahendar Ochani, Jianhua Li et al. · Proceedings of the National Academy of Sciences · 2003 · 1.1K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +14