Isolation and structure determination of a sesquiterpene lactone (vernodalinol) from<i>Vernonia amygdalina</i>extracts

Abstract

Vernodalinol structure was confirmed using a battery of spectroscopic methods, 1D and 2D NMR, high-resolution mass spectrometry (HR-MS), UV, IR, and X-ray. These results suggest that vernodalinol, although it has some biological activity, is likely to work in concert with other ingredients responsible for the anticancer activity exhibited of VA.