RSC Advances · 2012 · 12 citations · 13 references
MedicineMedicinal ChemistryPharmacologyGreen ChemistryOrganic ChemistrySynthetic Medicinal ChemistryAntibacterial AgentsAntibacterial PharmacologyAntibacterial TherapyRetrosynthetic AnalysisAntibacterial Drug DevelopmentAntimalarial AgentsAntimalarial Drug DevelopmentAtom Economy ImprovementAtom Economy In Coupling ReactionsNovel Antibacterial AgentsNovel Antibacterial Drug DiscoverySynthetic Antiparasitic Compounds
An efficient and rapid synthesis of antiplasmodial and antibacterial agent CJ-15,801 and its isomer cis-CJ-15,801 is disclosed. We have made an attempt towards “Ideal Synthesis” or a step towards “Dial-a-Molecule” by reducing the number of steps, following atom economy, and a green synthetic route.
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Aiming for the Ideal Synthesis
Tanja Gaich, Phil S. Baran · The Journal of Organic Chemistry · 2010 · 649 citations