Metabolic acidemia with hypoxia attenuates the hemodynamic responses to epinephrine during resuscitation in lambs

Abstract

During the physiologic conditions associated with neonatal resuscitation, that is, hypoxia with a compromised hemodynamic state, metabolic acidemia significantly attenuates the hemodynamic responses to resuscitation with epinephrine and oxygen. Correction of metabolic acidosis may be warranted in newborn resuscitation.