Concepedia

Isolation and Reactions of the Lithium Di-enolate of Diethyl Succinate

Nathan R. Long, Michael W. Rathke

Synthetic Communications · 1981 · 20 citations · 7 references

DOI

Concepts

Abstract

Abstract The Stobbe condensation1 is a classical reaction of the mono-enolate, l, of diethyl succinate, generated in situ by action of alkoxide bases, with aldehydes or ketones (eq 1).

References

7

Reaction of lithium N-isopropylcyclohexylamide with esters. Method for the formation and alkylation of ester enolates

Michael W. Rathke, Andreas Lindert · Journal of the American Chemical Society · 1971 · 167 citations

, , +5

The dianion of dimethyl cyclobut-3-ene-1,2-dicarboxylate. Aromaticity vs. Coulombic repulsion

Peter J. Garratt, Robert Zahler · Journal of the American Chemical Society · 1978 · 43 citations

, , +6

Dehydrogenation and coupling reactions in the presence of iodine and molten salt hydrogen iodide acceptors

Charles T. Adams, Stanley G. Brandenberger, J. B. DuBois et al. · The Journal of Organic Chemistry · 1977 · 27 citations

, , +8

Specific synthesis and selective alkylation and condensation of monoesters of substituted succinic acids

William G. Kofron, Lawson G. Wideman · The Journal of Organic Chemistry · 1972 · 23 citations

, , +7

Stereospecificity in alkylation of anions of ketone dimethylhydrazones: kinetic preference, thermodynamic preference

Michael E. Jung, Teresa J. Shaw · Tetrahedron Letters · 1977 · 23 citations

, , +14