Up-Regulation of IRAK-M is Essential for Endotoxin Tolerance Induced by a Low Dose of Lipopolysaccharide in Kupffer Cells

IRAK-M Is a Negative Regulator of Toll-like Receptor Signaling

Koichi S. Kobayashi, Lorraine D. Hernandez, Jorge E. Galán et al. · Cell · 2002 · 1.3K citations · Full text

Life Sciences, Cell Biology, Immunology +14

Inhibition of Lipopolysaccharide-Induced Signal Transduction in Endotoxin-Tolerized Mouse Macrophages: Dysregulation of Cytokine, Chemokine, and Toll-Like Receptor 2 and 4 Gene Expression

Andrei E. Medvedev, Karen M. Kopydlowski, Stefanie N. Vogel · The Journal of Immunology · 2000 · 513 citations

Life Sciences, Immunology, Molecular Biology +17

Induction of Cross-Tolerance by Lipopolysaccharide and Highly Purified Lipoteichoic Acid Via Different Toll-Like Receptors Independent of Paracrine Mediators

Martin D. Lehner, Siegfried Morath, Kathrin S. Michelsen et al. · The Journal of Immunology · 2001 · 290 citations

Life Sciences, Immunology, Microbiology +17

Dysregulation of LPS-Induced Toll-Like Receptor 4-MyD88 Complex Formation and IL-1 Receptor-Associated Kinase 1 Activation in Endotoxin-Tolerant Cells

Andrei E. Medvedev, Arnd Lentschat, Larry M. Wahl et al. · The Journal of Immunology · 2002 · 272 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Review: Molecular mechanisms of endotoxin tolerance

Hongkuan Fan, James A. Cook · Journal of Endotoxin Research · 2004 · 265 citations

Life Sciences, Immunology, Cell Signaling +16