Highly selective fluorescence imaging of zinc distribution in HeLa cells and Arabidopsis using a naphthalene-based fluorescent probe

Ji Ha Lee, Jin Hyeok Lee, Sung Ho Jung, Tae Kyung Hyun, Mingxiao Feng, Jae-Yean Kim

Chemical Communications · 2015 · 58 citations · 20 references

Abstract

2-(N,N-Dimethylamino)naphthalene-based probe 1 was found to exhibit a dramatic enhancement in fluorescence upon addition of Zn(2+), but not with any other metal ions. Probe 1 as a chemoprobe enabled high-resolution fluorescence imaging of zinc ions in HeLa cells and Arabidopsis.

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