Cerebellar diffuse amyloid plaques are derived from dendritic Aβ42 accumulations in Purkinje cells

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

Colin L. Masters, G. Simms, Nicola A. Weinman et al. · Proceedings of the National Academy of Sciences · 1985 · 4.4K citations · Full text

Down Syndrome, Neurodegenerative Diseases, Alzheimer's Disease +15

Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43)

Takeshi Iwatsubo, Asano Odaka, Nobuhiro Suzuki et al. · Neuron · 1994 · 1.7K citations

Alzheimer's Disease, Dementia, Pathology +9

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

Philippe Séguéla, Jacques I. Wadiche, Kelly Dineley‐Miller et al. · Journal of Neuroscience · 1993 · 1.5K citations · Full text

Nicotinic Cation Channel, Functional Properties, Neurotransmitter +19

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

K. E. Wisniewski, Henryk M. Wı́sniewski, G. Y. Wen · Annals of Neurology · 1985 · 1.2K citations

Intraneuronal Aβ42 Accumulation in Human Brain

Gunnar K. Gouras, Julia Tsai, Jan Näslund et al. · American Journal Of Pathology · 2000 · 986 citations · Full text

Neurodegenerative Diseases, Degenerative Pathology, Intraneuronal Aβ42 Accumulation +6