Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

Harry T. Haigler, Frederick R. Maxfield, Mark C. Willingham et al. · Journal of Biological Chemistry · 1980 · 794 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

Jerry Lin, William Ju, Kelly A. Foster et al. · Nature Neuroscience · 2000 · 555 citations

Life Sciences, Molecular Biology, Neuroscience +16

Palonosetron improves prevention of chemotherapy-induced nausea and vomiting following moderately emetogenic chemotherapy: results of a double-blind randomized phase III trial comparing single doses of palonosetron with ondansetron

Richard J. Gralla, M. Lichinitser, S. van der Vegt et al. · Annals of Oncology · 2003 · 471 citations

Medicine, Oncology, Pharmacology +17

Improved prevention of moderately emetogenic chemotherapy‐induced nausea and vomiting with palonosetron, a pharmacologically novel 5‐HT₃ receptor antagonist

Peter D. Eisenberg, Jazmin Figueroa‐Vadillo, Rosalio Zamora et al. · Cancer · 2003 · 404 citations · Full text

Medicine, Oncology, Pharmacology +17

A phase III, double-blind, randomized trial of palonosetron compared with ondansetron in preventing chemotherapy-induced nausea and vomiting following highly emetogenic chemotherapy

Matti Aapro, Steven M. Grunberg, George Manikhas et al. · Annals of Oncology · 2006 · 340 citations · Full text

Medicine, Oncology, Pharmacology +16