Cyclosporine in patients with steroid-resistant nephrotic syndrome: an open-label, nonrandomized, retrospective study

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

Nicolas Boute, Olivier Gribouval, Séverine Roselli et al. · Nature Genetics · 2000 · 1.4K citations

Medicine, Genetics, Nephrology +13

Mutations in ACTN4, encoding α-actinin-4, cause familial focal segmental glomerulosclerosis

Joshua M. Kaplan, Sung Hyun Kim, Kathryn N. North et al. · Nature Genetics · 2000 · 1.2K citations

Medicine, Genetics, Molecular Genetics +12

Patients with Mutations in NPHS2 (Podocin) Do Not Respond to Standard Steroid Treatment of Nephrotic Syndrome

Rainer Ruf, Anne Lichtenberger, Stephanie M. Karle et al. · Journal of the American Society of Nephrology · 2004 · 415 citations · Full text

Medicine, Genetics, Molecular Genetics +12

Structure of the Gene for Congenital Nephrotic Syndrome of the Finnish Type (NPHS1) and Characterization of Mutations

Ulla Lenkkeri, Minna Männikkö, Paula McCready et al. · The American Journal of Human Genetics · 1999 · 402 citations · Full text

Medicine, Genetics, Molecular Genetics +14

A randomized trial of cyclosporine in patients with steroid-resistant focal segmental glomerulosclerosis

Daniel Cattran, Gerald B. Appel, Lee A. Hebert et al. · Kidney International · 1999 · 323 citations

Medicine, Nephrology, Pharmacotherapy +13