Mathematical approach to thermolysin-catalyzed synthesis of aspartame precursor

Kinetics and equilibrium of enzymatic synthesis of peptides in aqueous/organic biphasic systems

Kazuhiro Nakanishi, Yukitaka Kimura, Ryuichi Matsuno · European Journal of Biochemistry · 1986 · 70 citations · Full text

Natural Sciences, Biochemistry, Chemistry +17

On the mechanism of the action of thermolysin: kinetic study of the thermolysin-catalysed condensation reaction of N-benzyloxycarbonyl-L-aspartic acid with L-phenylalanine methyl ester

Kiyotaka Oyama, Keiichi Kihara, Yuji Nonaka · Journal of the Chemical Society Perkin Transactions 2 · 1981 · 62 citations

Life Sciences, Biochemistry, Chemistry +14

Kinetics of aspartame precursor synthesis catalysed by <i>Pseudomonas aeruginosa</i> elastase

Kong H. Lee, Pat M. Lee, Yew S. Siaw et al. · Journal of Chemical Technology & Biotechnology · 1993 · 19 citations

Life Sciences, Biochemistry, Microbiology +13

Synthesis of aspartame precursor: α‐<scp>L</scp>‐aspartyl‐<scp>L</scp>‐phenylalanine methyl ester in ethyl acetate using thermolysin entrapped in polyurethane

Chin‐Pin Yang, Chein‐Shyong Su · Biotechnology and Bioengineering · 1988 · 12 citations

Life Sciences, Biochemistry, Chemistry +12