Multiple sclerosis associated amino acids of polymorphic regions relevant for the HLA antigen binding are confined to HLA-DR2

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

Charles M. Poser, Donald W. Paty, Labe C. Scheinberg et al. · Annals of Neurology · 1983 · 7.4K citations

Life Sciences, Neurology, Neuroscience +12

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

Henrik Zetterquist · Tissue Antigens · 1992 · 1.8K citations

Life Sciences, Genetics, Immunology +17

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

Lawrence J. Stern, Jerry H. Brown, Theodore S. Jardetzky et al. · Nature · 1994 · 1.6K citations

Life Sciences, Biochemistry, Immunology +17

Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein

Kai W. Wucherpfennig, Jack L. Strominger · Cell · 1995 · 1.5K citations · Full text

Life Sciences, Immunology, Pathology +17

A full genome search in multiple sclerosis

George C. Ebers, Kim Kukay, Dennis E. Bulman et al. · Nature Genetics · 1996 · 663 citations

Life Sciences, Genetics, Neurology +7