Synthetic Communications · 1994 · 23 citations · 3 references
Abstract Pyrimidine-5-carboxaldehyde was prepared in a one-pot reaction from 5-bromo-pyrimidine via metal halogen exchange. Pyrimidin-5-yl-lithium reacted with formate ester and ethyl cyanoformate, forming respectively the aldehyde and carboxy ethyl ester.
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The chemistry of organolithium compounds
Harry Heaney · Polymer · 1975 · 452 citations
The Reaction of 5-Bromo- and 2-Bromopyrimidine with Organolithium Compounds.
Salo Gronowitz, Irma Sinkkonen, J. Brunvoll et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1965 · 41 citations · Full text
1016. Reactions of pyrimidin-5-yl-lithium compounds
M. P. L. CATON, M. S. Grant, D. L. Pain et al. · Journal of the Chemical Society (Resumed) · 1965 · 18 citations