Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

Maj-Linda B. Selenica, Milene L. Brownlow, Jeffy P. Jimenez et al. · Neurodegenerative Diseases · 2012 · 10.4K citations · Full text

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Benoit Dérijard, Masahiko Hibi, I‐Huan Wu et al. · Cell · 1994 · 3.2K citations

Signal Transduction, Signaling Pathway, Cell Regulation +14

Oxidative Damage Is the Earliest Event in Alzheimer Disease

Akihiko Nunomura, George Perry, Gjumrakch Aliev et al. · Journal of Neuropathology & Experimental Neurology · 2001 · 1.8K citations · Full text

Blood‐brain barrier‐specific properties of a human adult brain endothelial cell line

Babette Weksler, Eva-Anne Subileau, Nicolas Perrière et al. · The FASEB Journal · 2005 · 1.3K citations

T-regulatory Cell, Immunology, Blood Cell +23

Activation of microglial cells by β-amyloid protein and interferon-γ

Lucia Meda, Marco A. Cassatella, Györgyi I. Szendrei et al. · Nature · 1995 · 1.3K citations

Inflammation, Medicine, Brain-immune Interaction +6