High-dose humanized anti-IL-2 receptor alpha antibody (daclizumab) for the treatment of active, non-infectious uveitis

Interleukin-2–Receptor Blockade with Daclizumab to Prevent Acute Rejection in Renal Transplantation

F. Vincenti, Robert L. Kirkman, Susan Light et al. · New England Journal of Medicine · 1998 · 876 citations · Full text

Medicine, Immunology, Pharmacology +17

TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

Ahjoku Amadi‐Obi, Cheng‐Rong Yu, Xuebin Liu et al. · Nature Medicine · 2007 · 849 citations

Medicine, Immunology, Pathology +12

Standardizatlon of Vitreal inflammatory Activity in Intermediate and Posterior Uveitis

Robert B. Nussenblatt, Alan G. Palestine, Chi‐Chao Chan et al. · Ophthalmology · 1985 · 681 citations

Medicine, Ophthalmology, Inflammation +13

Regulatory CD56 ^bright natural killer cells mediate immunomodulatory effects of IL-2Rα-targeted therapy (daclizumab) in multiple sclerosis

Bibiana Bielekova, Marta Catálfamo, Susan Reichert-Scrivner et al. · Proceedings of the National Academy of Sciences · 2006 · 593 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +17

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.

Rachel R Caspi, François Roberge, C.–C. Chan et al. · The Journal of Immunology · 1988 · 461 citations

Medicine, Immunology, Ophthalmology +17