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HO-1 and JAK-2/STAT-1 signals are involved in preferential inhibition of iNOS over COX-2 gene expression by newly synthesized tetrahydroisoquinoline alkaloid, CKD712, in cells activated with lipopolysacchride

Medicinal ChemistryAnti-inflammatorySignal TransductionJak-2/stat-1 SignalsBiochemistryTetrahydroisoquinoline AlkaloidMedicineNatural SciencesLipid PeroxidationReceptor Tyrosine KinaseOxysterolCell DeathMechanism Of ActionPharmacologyCell BiologyCox-2 Gene ExpressionDrug DiscoveryOxidative Stress