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The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways

BiologyAntiparasitic AgentMedicineParasitic ProtozoaHydrogenosomal Enzymatic PathwaysFlavin ReductaseMicrobiologyHost ResistancePharmacologyAntimicrobial ResistanceDrug Resistance