David Leitsch - Concepedia

Author

David Leitsch

Medical University of Vienna ORCID

Also Known As

D. Leitsch, David Leitsch

141

Publications

2.4K

Citations

H-Index

Concepts

All Affiliations

Medical University of Vienna BOKU University University of Bern University of Szeged University of Veterinary Medicine Vienna

About

David Leitsch is an author at Medical University of Vienna specializing in medicine, microbiology, and drug resistance.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	13	15	835
2	Natural Sciences	6	6	431
3	Health Sciences	4	4	107
4	Education	1	1	60
5	Public Health	1	1	27

David Leitsch

Publications

1.9K

Citations

H-Index

Page 1

	Year	Citations
<i>Trichomonas vaginalis</i>: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance David Leitsch, Daniel Kolarich, Marina Binder, Molecular Microbiology Antiparasitic AgentRedox BiologyThioredoxin PeroxidaseCellular Redox SystemToxicological Mechanism	2009	167
RNA chaperone activity of the Sm‐like Hfq protein Isabella Moll, David Leitsch, Tanja Steinhauser, EMBO Reports Natural SciencesRna BiologyMolecular BiologyChaperonesRna Chaperone Activity	2003	155
Nitroimidazole Action in Entamoeba histolytica: A Central Role for Thioredoxin Reductase David Leitsch, Daniel Kolarich, Iain B. H. Wilson, PLoS Biology Bioorganic ChemistryAntiparasitic AgentRedox BiologyDrug ResistanceReactive Nitrogen Specie	2007	147
A Reprofiled Drug, Auranofin, Is Effective against Metronidazole-Resistant Giardia lamblia Noa Tejman-Yarden, Yukiko Miyamoto, David Leitsch, Antimicrobial Agents and Chemotherapy Chemical LibraryGiardia LambliaAntiparasitic AgentParasitic ProtozoaDiarrheal Disease Worldwide	2013	142
Pyruvate:ferredoxin oxidoreductase and thioredoxin reductase are involved in 5-nitroimidazole activation while flavin metabolism is linked to 5-nitroimidazole resistance in Giardia lamblia David Leitsch, Anita G. Burgess, Linda A. Dunn, Journal of Antimicrobial Chemotherapy	2011	130
Recent Advances in the Trichomonas vaginalis Field David Leitsch F1000Research	2016	83
<i><scp>T</scp>richomonas vaginalis</i> flavin reductase 1 and its role in metronidazole resistance David Leitsch, Brian D. Janssen, Daniel Kolarich, Molecular Microbiology	2013	82
Major Role for Cysteine Proteases during the Early Phase of Acanthamoeba castellanii Encystment David Leitsch, Martina Köhsler, Martina Marchetti‐Deschmann, Eukaryotic Cell	2010	71
Validation of reference genes for the normalization of RT-qPCR gene expression in Acanthamoeba spp. Martina Köhsler, David Leitsch, Norbert Müller, Scientific Reports	2020	65
The flavin inhibitor diphenyleneiodonium renders Trichomonas vaginalis resistant to metronidazole, inhibits thioredoxin reductase and flavin reductase, and shuts off hydrogenosomal enzymatic pathways David Leitsch, Daniel Kolarich, Michael Duchêne Molecular and Biochemical Parasitology BiologyAntiparasitic AgentMedicineParasitic ProtozoaHydrogenosomal Enzymatic Pathways	2010	62

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