Sigma receptors modulate the hypothalamic-pituitary-adrenal (HPA) axis centrally: evidence for a functional interaction with NMDA receptors, in vivo

Statistical Principles in Experimental Design

Jerome L. Myers, B. J. Winer · The American Journal of Psychology · 1964 · 8.1K citations

Public Health, Biostatistics, Experimental Design +10

Pharmacological and autoradiographic discrimination of sigma and phencyclidine receptor binding sites in brain with (+)-[3H]SKF 10,047, (+)-[3H]-3-[3-hydroxyphenyl]-N-(1-propyl)piperidine and [3H]-1-[1-(2-thienyl)cyclohexyl]piperidine.

B L Largent, Andrew L. Gundlach, S H Snyder · Journal of Pharmacology and Experimental Therapeutics · 1986 · 348 citations · Full text

Medicine, Neurobiology, Pharmacology +12

σ-Receptors in Endocrine Organs: Identification, Characterization, and Autoradiographic Localization in Rat Pituitary, Adrenal, Testis, and Ovary

Seth A. Wolfe, Steven Culp, Errol B. De Souza · Endocrinology · 1989 · 159 citations

Medicine, Endocrinology, Pharmacology +8

Synthesis and evaluation of optically pure [³H]‐(+)‐pentazocine, a highly potent and selective radioligand for σ receptors

Brian R. de Costa, Wayne D. Bowen, Susan B. Hellewell et al. · FEBS Letters · 1989 · 141 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Kappa opiate agonists modulate the hypothalamic-pituitary-adrenocortical axis in the rat.

Satish Iyengar, H. S. Kim, Paul L. Wood · Journal of Pharmacology and Experimental Therapeutics · 1986 · 76 citations

Medicine, Endocrinology, Pharmacology +16