Central injection of IL-10 antagonizes the behavioural effects of lipopolysaccharide in rats

Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia.

Catherine Gérard, Catherine Bruyns, Arnaud Marchant et al. · The Journal of Experimental Medicine · 1993 · 800 citations · Full text

Veterinary Medicine, Immunology, Pharmacology +17

Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.

Daniel Berg, Ralf Kühn, Klaus Rajewsky et al. · Journal of Clinical Investigation · 1995 · 539 citations · Full text

Life Sciences, Immunology, Pathology +16

Peripheral administration of lipopolysaccharide induces the expression of cytokine transcripts in the brain and pituitary of mice

Sophie Layé, Patricia Parnet, Emmanuelle Goujon et al. · Molecular Brain Research · 1994 · 497 citations

Life Sciences, Immunology, Neuroscience +16

Interleukin‐10 prevents experimental allergic encephalomyelitis in rats

Ortwin Rott, Bernhard Fleischer, Evelyne Cash · European Journal of Immunology · 1994 · 369 citations

Life Sciences, Immunology, Pathology +17

Time course and localization patterns of interleukin-1β messenger rna expression in brain and pituitary after peripheral administration of lipopolysaccharide

Ning Quan, Michael Whiteside, Miles Herkenham · Neuroscience · 1998 · 337 citations

Life Sciences, Neurobiology, Neuroscience +16