Concepedia

Elgonica-Dimers A and B, Two Potent Alcohol Metabolism Inhibitory Constituents of <i>Aloe </i><i>arborescens</i>

Kuk Hyun Shin, Won Sick Woo, Soon Sung Lim, Chang Sub Shim, Ha Sook Chung, Edward J. Kennelly, A. Douglas Kinghorn

Journal of Natural Products · 1997 · 32 citations · 3 references

DOI

Concepts

Abstract

Activity-guided fractionation of the leaves of Aloe arborescens resulted in the isolation and characterization of the known compounds elgonica-dimers A ( 1 ) and B ( 2 ) as potent inhibitors of cytosolic alcohol dehydrogenase and aldehyde dehydrogenase activities in vitro.

References

3

Preferential inhibition of the low Km aldehyde dehydrogenase activity by pargyline

M.E. Lebsack, Dennis R. Petersen, Allan C. Collins et al. · Biochemical Pharmacology · 1977 · 45 citations

, , +12

Novel Anthrone-Anthraquinone Dimers from Aloe elgonica

J.M. Conner, Alexander I. Gray, Peter G. Waterman et al. · Journal of Natural Products · 1990 · 42 citations

, , +5

Spasmolytic Activity of Angelicin: A Coumarin from<i>Heracleum thomsoni</i><sup>1</sup>

G. K. Patnaik, Krishna Banaudha, Khalid Khan et al. · Planta Medica · 1987 · 41 citations

, , +9