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A Sugar‐Modified Phosphole Gold Complex with Antiproliferative Properties Acting as a Thioredoxin Reductase Inhibitor in MCF‐7 Cells
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Citations
21
References
2008
Year
Mcf‐7 CellsMolecular BiologyChemical BiologyThiosugar ComplexRedox BiologyOxidative StressMedicinal ChemistryAntiproliferative Properties ActingThioredoxin Reductase InhibitorBiochemistryThioredoxin Reductase InhibitionBiochemical InteractionPharmacologyProtein PhosphorylationReductive StressNatural SciencesMedicineDrug DiscoveryPhosphine-coordinated Gold
A phosphine-coordinated gold(I) thiosugar complex was found to exert potent cytotoxic and antiproliferative effects through thioredoxin reductase inhibition in MCF-7 cells.
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