ANTENATAL DIAGNOSIS OF SICKLE CELL ANAEMIA BY DIRECT ANALYSIS OF THE SICKLE MUTATION

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

Y Kan, A M Dozy · Proceedings of the National Academy of Sciences · 1978 · 801 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

ANTENATAL DIAGNOSIS OF SICKLE-CELL ANÆMIA BY D.N.A. ANALYSIS OF AMNIOTIC-FLUID CELLS

Yuet Wai Kan, AndréeM. Dozy · The Lancet · 1978 · 377 citations

Medicine, Maternal Health, Obstetrics +11

Base substitution in an intervening sequence of a beta+-thalassemic human globin gene.

Richard A. Spritz, Pudur Jagadeeswaran, Prabhakara V. Choudary et al. · Proceedings of the National Academy of Sciences · 1981 · 233 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Prenatal Diagnosis of Hemoglobinopathies

Blanche P. Alter, C. B. Modell, D. V. I. Fairweather et al. · New England Journal of Medicine · 1976 · 164 citations

Medicine, Maternal Health, Obstetrics +12